Chinese Journal of Respiratory and Critical Care Medicine
Supervisor：Ministry of Education of the People's Republic of ChinaSponsor：West China Medical Center & West China Hospital, Sichuan University Editor-in-chief：LIN Jiangtao / LIU Chuntao Publishing period：
Monthly
ISSN：1671-6205CN：51-1631/R
Objective To identify the incidence of postintubation hypotension (PIH) in critically ill patients and evaluate the responsive risk factors and prognosis.
Methods The data of intubation patients with normal blood pressure before intubation were collected and analyzed in Intensive Care Unit (ICU) in the latest two years and divided into two groups. One contained PIH patients and the other one contained patients with no change in blood pressure after intubation. The primary outcome measure was 28-day mortality and secondary outcome measure was length of stay (LOS) in ICU and hospital.
Results There were 25(31.65%) PIH patients in included 79 patients. The patients in PIH group had significantly higher 28-day mortality (40.00% vs 14.81%, P=0.01) and there were no difference in LOS in ICU and hospital. Risk factors were age (OR:1.1, 95% CI:1.00-1.12), chronic respiratory diseases (OR:3.0, 95% CI:1.13-8.07) and complication with over two chronic diseases (OR:3.6, 95% CI:1.18-11.03).
Conclusion PIH is more common in old patients complicated with chronic diseases and results in higher 28-day mortality.
Citation：WangWei, ZhouYu, SuZhenjiao, ZhengWei, ZhaoLing. The Risk Factors and Prognosis of Postintubation Hypotension in Critically Ill Patients. Chinese Journal of Respiratory and Critical Care Medicine, 2015, 14(5): 474-476. doi: 10.7507/1671-6205.2015115Copy
Copyright ? the editorial department of Chinese Journal of Respiratory and Critical Care Medicine of West China Medical Publisher. All rights reserved
1.
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Green RS, Edwards J, Sabri E, et al. Evaluation of the incidence, risk factors, and impact on patient outcomes of postintubation hemodynamic instability. CJEM, 2012, 14:74-82.
Heffner AC, Swords DS, Nussbaum ML, et al. Predictors of the complication of postintubation hypotension during emergency airway management. J Crit Care, 2012, 27:587-593.
9.
Lin CC, Chen KF, Shih CP, et al. The prognostic factors of hypotension after rapid sequence intubation. Am J Emerg Med, 2008, 26:845-851.
1. Reich DL, Hossain S, Krol M, et al. Predictors of hypotension after induction of general anesthesia. Anesth Analg, 2005, 101:622-628.
2. Heffner AC, Swords D, Kline JA, et al. The frequency and significance of postintubation hypotension during emergency airway management. J Crit Care, 2012, 27:417.e9-e13.
3. Griesdale DE, Bosma TL, Kurth T, et al. Complications of endotracheal intubation in the critically ill. Intensive Care Med, 2008, 34:1835-1842.
4. Green RS, Edwards J, Sabri E, et al. Evaluation of the incidence, risk factors, and impact on patient outcomes of postintubation hemodynamic instability. CJEM, 2012, 14:74-82.
8. Heffner AC, Swords DS, Nussbaum ML, et al. Predictors of the complication of postintubation hypotension during emergency airway management. J Crit Care, 2012, 27:587-593.
9. Lin CC, Chen KF, Shih CP, et al. The prognostic factors of hypotension after rapid sequence intubation. Am J Emerg Med, 2008, 26:845-851.
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Citation：WangWei, ZhouYu, SuZhenjiao, ZhengWei, ZhaoLing. The Risk Factors and Prognosis of Postintubation Hypotension in Critically Ill Patients. Chinese Journal of Respiratory and Critical Care Medicine, 2015, 14(5): 474-476. doi: 10.7507/1671-6205.2015115
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