“慢性阻塞性氣道疾病”之新概念：“三環圖”之新解_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

郭文佳 ,  牟向東

清華大學臨床醫學院，清華大學附屬北京清華長庚醫院，呼吸與危重癥醫學科（北京 102218）;

Corresponding?author：

牟向東, Email: muxiangdong@medmail.com.cn

Keywords：

DOI：

10.7507/1671-6205.202410084

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Citation： 郭文佳, 牟向東. “慢性阻塞性氣道疾病”之新概念：“三環圖”之新解. Chinese Journal of Respiratory and Critical Care Medicine, 2025, 24(3): 153-156. doi: 10.7507/1671-6205.202410084 Copy

1.	何權瀛. 對于慢性支氣管炎、肺氣腫和支氣管哮喘三環圖的一些困惑. 中國呼吸與危重監護雜志, 2024, 23(8): 533-536.
2.	American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 1995, 152(5 Pt 2): S77-121.
3.	Upadhyay P, Wu CW, Pham A, et al. Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD). J Toxicol Environ Health B Crit Rev, 2023, 26(5): 275-305.
4.	Jarhyan P, Hutchinson A, Khaw D, et al. Prevalence of chronic obstructive pulmonary disease and chronic bronchitis in eight countries: a systematic review and meta-analysis. Bull World Health Organ, 2022, 100(3): 216-230.
5.	Baltazar-Garcia EA, Vargas-Guerrero B, Gasca-Lozano LE, et al. Molecular changes underlying pulmonary emphysema and chronic bronchitis in Chronic Obstructive Pulmonary Disease: An updated review. Histol Histopathol, 2024, 39(7): 805-816.
6.	楊汀, 王辰. 支氣管哮喘氣道重構的機制及對氣道生理功能的影響. 國際呼吸雜志, 2002, 22(5): 258-260.
7.	鄭慧珍, 姜霽津, 毛貝等. 支氣管擴張癥研究年度進展2022. 中華醫學雜志, 2023, 103(8): 623-627.
8.	張黎莎, 王佳怡, 徐金富等. 支氣管擴張癥研究年度進展2023. 中華結核和呼吸雜志, 2024, 47(2): 152-156.
9.	O'Donnell AE. Bronchiectasis - A Clinical Review. N Engl J Med, 2022, 387(6): 533-545.
10.	LaFon DC, Dransfield MT. Bronchiectasis-Chronic Obstructive Pulmonary Disease Overlap: A ROSE by Any Other Name? Am J Respir Crit Care Med, 2024, 210(1): 20-21.
11.	Ni Y, Shi G, Yu Y, et al. Clinical characteristics of patients with chronic obstructive pulmonary disease with comorbid bronchiectasis: a systemic review and meta-analysis. Int J Chron Obstruct Pulmon Dis, 2015, 10: 1465-1475.
12.	Keir HR, Shoemark A, Dicker AJ, et al. Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study. Lancet Respir Med, 2021, 9(8): 873-884.
13.	Metersky ML, Dransfield MT. The chronic obstructive pulmonary disease (COPD)-bronchiectasis overlap syndrome: does my COPD patient have bronchiectasis on computed tomography? "Frankly, my dear, I don't give a damn!". Am J Respir Crit Care Med, 2023, 208(12): 1265-1267.
14.	Sobala R, De Soyza A. Bronchiectasis and chronic obstructive pulmonary disease overlap syndrome. Clin Chest Med, 2022, 43(1): 61-70.
15.	Heffernan A, Shafiee A, Chan T, et al. Non‐type 2 and mixed inflammation in chronic rhinosinusitis and lower airway disease. Laryngoscope, 2024, 134(3): 1005-1013.
16.	Polverino E, Dimakou K, Traversi L, et al. Bronchiectasis and asthma: data from the European Bronchiectasis Registry (EMBARC). J Allergy Clin Immunol, 2024, 153(6): 1553-1562.
17.	Tiotiu A, Martinez-Garcia MA, Mendez-Brea P, et al. Does asthma-bronchiectasis overlap syndrome (ABOS) really exist? J Asthma, 2023, 60(11): 1935-1941.
18.	郭文佳, 牟向東, 徐文帥, 等. 支氣管擴張合并慢性鼻竇炎相關疾病的研究進展. 北京醫學, 2023, 45(4): 340-342.
19.	Zhang XX, He JH, Pan CX, et al. Bacteria and viruses and clinical outcomes of asthma-bronchiectasis overlap syndrome: a cohort study. Clin Transl Allergy, 2024, 14(1): e12331.
20.	何權瀛. 2022年版GOLD慢性阻塞性肺疾病診斷、治療及預防全球策略解析. 中國醫藥導刊, 2022, 24(2): 111-115.
21.	Agusti A, Celli BR, Criner GJ, et al. Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. Eur Respir J, 2023, 61(4): 2300239.
22.	Yang IA, Jenkins CR, Salvi SS. Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment. Lancet Respir Med, 2022, 10(5): 497-511.

1. 何權瀛. 對于慢性支氣管炎、肺氣腫和支氣管哮喘三環圖的一些困惑. 中國呼吸與危重監護雜志, 2024, 23(8): 533-536.
2. American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 1995, 152(5 Pt 2): S77-121.
3. Upadhyay P, Wu CW, Pham A, et al. Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD). J Toxicol Environ Health B Crit Rev, 2023, 26(5): 275-305.
4. Jarhyan P, Hutchinson A, Khaw D, et al. Prevalence of chronic obstructive pulmonary disease and chronic bronchitis in eight countries: a systematic review and meta-analysis. Bull World Health Organ, 2022, 100(3): 216-230.
5. Baltazar-Garcia EA, Vargas-Guerrero B, Gasca-Lozano LE, et al. Molecular changes underlying pulmonary emphysema and chronic bronchitis in Chronic Obstructive Pulmonary Disease: An updated review. Histol Histopathol, 2024, 39(7): 805-816.
6. 楊汀, 王辰. 支氣管哮喘氣道重構的機制及對氣道生理功能的影響. 國際呼吸雜志, 2002, 22(5): 258-260.
7. 鄭慧珍, 姜霽津, 毛貝等. 支氣管擴張癥研究年度進展2022. 中華醫學雜志, 2023, 103(8): 623-627.
8. 張黎莎, 王佳怡, 徐金富等. 支氣管擴張癥研究年度進展2023. 中華結核和呼吸雜志, 2024, 47(2): 152-156.
9. O'Donnell AE. Bronchiectasis - A Clinical Review. N Engl J Med, 2022, 387(6): 533-545.
10. LaFon DC, Dransfield MT. Bronchiectasis-Chronic Obstructive Pulmonary Disease Overlap: A ROSE by Any Other Name? Am J Respir Crit Care Med, 2024, 210(1): 20-21.
11. Ni Y, Shi G, Yu Y, et al. Clinical characteristics of patients with chronic obstructive pulmonary disease with comorbid bronchiectasis: a systemic review and meta-analysis. Int J Chron Obstruct Pulmon Dis, 2015, 10: 1465-1475.
12. Keir HR, Shoemark A, Dicker AJ, et al. Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study. Lancet Respir Med, 2021, 9(8): 873-884.
13. Metersky ML, Dransfield MT. The chronic obstructive pulmonary disease (COPD)-bronchiectasis overlap syndrome: does my COPD patient have bronchiectasis on computed tomography? "Frankly, my dear, I don't give a damn!". Am J Respir Crit Care Med, 2023, 208(12): 1265-1267.
14. Sobala R, De Soyza A. Bronchiectasis and chronic obstructive pulmonary disease overlap syndrome. Clin Chest Med, 2022, 43(1): 61-70.
15. Heffernan A, Shafiee A, Chan T, et al. Non‐type 2 and mixed inflammation in chronic rhinosinusitis and lower airway disease. Laryngoscope, 2024, 134(3): 1005-1013.
16. Polverino E, Dimakou K, Traversi L, et al. Bronchiectasis and asthma: data from the European Bronchiectasis Registry (EMBARC). J Allergy Clin Immunol, 2024, 153(6): 1553-1562.
17. Tiotiu A, Martinez-Garcia MA, Mendez-Brea P, et al. Does asthma-bronchiectasis overlap syndrome (ABOS) really exist? J Asthma, 2023, 60(11): 1935-1941.
18. 郭文佳, 牟向東, 徐文帥, 等. 支氣管擴張合并慢性鼻竇炎相關疾病的研究進展. 北京醫學, 2023, 45(4): 340-342.
19. Zhang XX, He JH, Pan CX, et al. Bacteria and viruses and clinical outcomes of asthma-bronchiectasis overlap syndrome: a cohort study. Clin Transl Allergy, 2024, 14(1): e12331.
20. 何權瀛. 2022年版GOLD慢性阻塞性肺疾病診斷、治療及預防全球策略解析. 中國醫藥導刊, 2022, 24(2): 111-115.
21. Agusti A, Celli BR, Criner GJ, et al. Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. Eur Respir J, 2023, 61(4): 2300239.
22. Yang IA, Jenkins CR, Salvi SS. Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment. Lancet Respir Med, 2022, 10(5): 497-511.

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“慢性阻塞性氣道疾病”之新概念：“三環圖”之新解

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