慢性阻塞性肺疾病風險因素的研究進展_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

呂垚 ¹ , 張瑞 ^1,2 , 崔慧杰 ² , 陳楚萍 ¹ , 劉璇 ² ,  雷弋 ^1,2 ,  李為民 ²

1. ;
2. ;

Corresponding?author：

雷弋, Email: leiyi111@scu.edu.cn; 李為民, Email: weimi003@scu.edu.cn

Keywords：

DOI：

10.7507/1671-6205.202506051

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Citation： 呂垚, 張瑞, 崔慧杰, 陳楚萍, 劉璇, 雷弋, 李為民. 慢性阻塞性肺疾病風險因素的研究進展. Chinese Journal of Respiratory and Critical Care Medicine, 2026, 25(2): 142-147. doi: 10.7507/1671-6205.202506051 Copy

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29.	Lee SH, Hwang ED, Lim JE, et al. The Risk Factors and Characteristics of COPD Among Nonsmokers in Korea: An Analysis of KNHANES IV and V. Lung. 2016;194(3): 353-361.
30.	Gupte AN, Paradkar M, Selvaraju S, et al. Assessment of lung function in successfully treated tuberculosis reveals high burden of ventilatory defects and COPD. PloS one. 2019;14(5): e0217289.
31.	Allwood BW, Gillespie R, Galperin-Aizenberg M, et al. Obstructive pulmonary disease in patients with previous tuberculosis: Pathophysiology of a community-based cohort. S Afr Med J. 2017;107(5): 440-445.
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38.	Agusti A, Faner R. Lung function trajectories in health and disease. Lancet Respir Med. 2019;7(4): 358-364.
39.	Lange P, Celli B, Agustí A, et al. Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease. N Engl J Med. 2015;373(2): 111-122.
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41.	Bui DS, Perret JL, Walters EH, et al. Association between very to moderate preterm births, lung function deficits, and COPD at age 53 years: analysis of a prospective cohort study. Lancet Respir Med. 2022;10(5): 478-484.
42.	尤巧云. 958例慢性阻塞性肺疾病高危人群風險因素及中醫證候學特征研究. 安徽中醫藥大學, 2023.
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52.	肖心儒, 施宇佳, 張倩. 慢性阻塞性肺疾病生物學標志物的研究進展南京醫科大學學報(自然科學版). 2023;43(7): 1011-1016+1021.
53.	Wei Y, Wang S, Wang D, et al. Expression and clinical significance of serum amyloid A and interleukin-6 in patients with acute exacerbation of chronic obstructive pulmonary disease. Exp Ther Med. 2020;19(3): 2089-2094.
54.	Garudadri S, Woodruff PG, Han MK, et al. Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved Spirometry in SPIROMICS. Chest. 2019;155(5): 908-917.
55.	2025 GOLD report[EB/OL]. [2025-12-16]. https://goldcopd.org/2025-gold-report/.
56.	中華醫學會呼吸病學分會肺功能學組. 成人肺功能檢查技術進展及臨床應用推薦指南(2025版)[J/OL]中華肺部疾病雜志(電子版), 2025, 18(02): 197-212.
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1.
2.
3.
4. GBD 2023 Causes of Death Collaborators. Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023. Lancet. 2025 ;406(10513): 1811-1872.
5. Wang C, Xu J, Yang L, et al. Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study. Lancet. 2018;391(10131): 1706-1717.
6.
7.
8.
9.
10. Yang IA, Jenkins CR, Salvi SS. Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment. Lancet Respir Med. 2022;10(5): 497-511.
11.
12.
13.
14.
15.
16.
17.
18.
19. Apte K, Salvi S. Household air pollution and its effects on health. F1000Research. 2016;5.
20.
21.
22.
23.
24.
25.
26.
27. Leung C, Sin DD. Asthma-COPD overlap: What are the important questions? Chest, 2022, 161(2): 330-344.
28. Bisgaard H, N?rgaard S, Sevelsted A, et al. Asthma-like symptoms in young children increase the risk of COPD. J Allergy Clin Immunol, 2021, 147(2): 569-576. e5.
29. Lee SH, Hwang ED, Lim JE, et al. The Risk Factors and Characteristics of COPD Among Nonsmokers in Korea: An Analysis of KNHANES IV and V. Lung. 2016;194(3): 353-361.
30. Gupte AN, Paradkar M, Selvaraju S, et al. Assessment of lung function in successfully treated tuberculosis reveals high burden of ventilatory defects and COPD. PloS one. 2019;14(5): e0217289.
31. Allwood BW, Gillespie R, Galperin-Aizenberg M, et al. Obstructive pulmonary disease in patients with previous tuberculosis: Pathophysiology of a community-based cohort. S Afr Med J. 2017;107(5): 440-445.
32.
33.
34.
35. S?rheim IC, Johannessen A, Gulsvik A, et al. Gender differences in COPD: are women more susceptible to smoking effects than men? Thorax, 2010, 65(6): 480-485.
36.
37.
38. Agusti A, Faner R. Lung function trajectories in health and disease. Lancet Respir Med. 2019;7(4): 358-364.
39. Lange P, Celli B, Agustí A, et al. Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease. N Engl J Med. 2015;373(2): 111-122.
40.
41. Bui DS, Perret JL, Walters EH, et al. Association between very to moderate preterm births, lung function deficits, and COPD at age 53 years: analysis of a prospective cohort study. Lancet Respir Med. 2022;10(5): 478-484.
42. 尤巧云. 958例慢性阻塞性肺疾病高危人群風險因素及中醫證候學特征研究. 安徽中醫藥大學, 2023.
43.
44. Hernández Pérez JM. Alpha1-Antitrypsin Deficiency. N Engl J Med, 2024, 22;391(8): e16.
45.
46.
47.
48.
49. 林秀, 林凱洵, 徐海紅, 等. 慢性阻塞性肺疾病篩查工具的研究進展實用心腦肺血管病雜志. 2025;33(1): 132-137.
50.
51.
52. 肖心儒, 施宇佳, 張倩. 慢性阻塞性肺疾病生物學標志物的研究進展南京醫科大學學報(自然科學版). 2023;43(7): 1011-1016+1021.
53. Wei Y, Wang S, Wang D, et al. Expression and clinical significance of serum amyloid A and interleukin-6 in patients with acute exacerbation of chronic obstructive pulmonary disease. Exp Ther Med. 2020;19(3): 2089-2094.
54. Garudadri S, Woodruff PG, Han MK, et al. Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved Spirometry in SPIROMICS. Chest. 2019;155(5): 908-917.
55. 2025 GOLD report[EB/OL]. [2025-12-16]. https://goldcopd.org/2025-gold-report/.
56. 中華醫學會呼吸病學分會肺功能學組. 成人肺功能檢查技術進展及臨床應用推薦指南(2025版)[J/OL]中華肺部疾病雜志(電子版), 2025, 18(02): 197-212.
57.
58.
59.
60.
61.

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