慢性咳嗽在人群的發生率為3%~40%。導致慢性咳嗽的主要原因是上氣道咳嗽綜合征(UACS)、哮喘和胃食管反流病(GERD) 。也有學者將UACS簡化為鼻炎,體現了以鼻腔和鼻竇炎性疾病為代表的上氣道疾病對慢性咳嗽的病因學意義。診療非吸煙、未服用血管緊張素轉化酶(ACE)抑制劑的慢性咳嗽患者,應首先考慮上述三大類疾病,可以單獨或聯合存在。由于臨床癥狀可能僅表現為咳嗽,同時,病史中提示性的線索通常有限,都可能增加診斷的難度。
Citation:
ZHANG Luo,WANG Xiaodong,HAN Demin. Nasal diseases and upper airway cough syndrome. Chinese Journal of Respiratory and Critical Care Medicine, 2008, 08(6): 404-407. doi:
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- 2. Pratter MR.Ove~iew of common caases of chronic COUgh:ACCP evidence—based clinical practice guidelines.Chest,2006,129(1 Supp1):59S-62S.
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- 4. 張羅,韓德民,王琪.鼻炎概述.中國耳鼻咽喉頭頸外科,2007, 14:19-24.
- 5. 韓德民,張羅,黃丹,等.我國l1城市變應性鼻炎自報患病率調查.中華耳鼻咽喉頭頸外科雜志,2007,42:83-89.
- 6. Bousquet J,Khahaev N,Cruz AA,et al.Allergic Rhinitis and its Impact on A~hma(ARIA)2008 update(in collaboration with the rId Health Organization,GA(2)LEN and AllerGen).Allergy.
- 7. 張羅,韓德民.解讀2008年新版變應性鼻炎及其對哮喘的影響.中華耳鼻咽喉頭頸外科雜志,2008,43:552-557..
- 8. ,63(Suppl 86):8-160.