白細胞介素17A在哮喘發病機制中的研究進展_Chinese Journal of Respiratory and Critical Care Medicine

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龔雨新 , 于化鵬

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Citation： 龔雨新,于化鵬. 白細胞介素17A在哮喘發病機制中的研究進展. Chinese Journal of Respiratory and Critical Care Medicine, 2009, 09(2): 199-201. doi: Copy

1.	Katoh S, Kitazawa H, Shimosato T, et al. Cloning and characterization of Swine interleukin-17, preferentially expressed in the intestines. J Interferon Cytokine Res, 2004, 24: 553-559.
2.	Li TS, Li XN, Chang ZJ, et al. Identification and functional characterization of a novel interleukin 17 receptor: a possible mitogenic activation through ras /mitogen-activated protein kinase signaling pathway. Cell Signal, 2006, 18: 1287-1298.
3.	Rahman MS, Yamasaki A, Yang J, et al. IL-17A induces eotaxin-1 /CC chemokine ligand 11 expression in human airway smooth muscle cells: role ofMAPK ( Erk1/2, JNK, and p38) pathways. J Immunol,2006, 177: 4064-4071.
4.	Patel DN, King CA, Bailey SR, et al. Interleukin-17 stimulates Creactive protein expression in hepatocytes and smooth muscle cells via p38MAPK and ERK1 /2-dependent NF-kappaB and C/EBPbeta activation. J Biol Chem, 2007, 282: 27229-27238.
5.	Ferretti S, Bonneau O, Dubois GR, et al. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharideinduced airway neutrophilia: IL-15 as a possible trigger. J Immunol,2003, 170: 2106-2112.
6.	Miljkovic DJ, Cvetkovic I, Vuckovic O, et al. The role of interleukin-17 in inducible nitric oxide synthase-mediated nitric oxide production in endothelial cells. Cell Mol Life Sci, 2003, 60 : 518 -525.
7.	Henness S, van Thoor E, Ge Q, et al. IL-17A acts via p38 MAPK to increase stability of TNF-alpha-induced IL-8 mRNA in human ASM. Am J Physiol Lung Cell Mol Physiol, 2006, 290: L1283-L1290 .
8.	Kao CY, Huang F, Chen Y, et al. Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/ NF-kappaB-dependent signaling pathway. J Immunol, 2005, 175: 6676-6685.
9.	Happel KI, Zheng M, Young E, et al. Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection. J Immunol, 2003, 170: 4432-4436.
10.	Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17 -producing CD4 + effector T cells develop via a liesge distinct from the T helper type 1 and lineages. Nat Immunol, 2005, 6: 123-132.
11.	Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol, 2005, 6: 1133-1141.
12.	Wilson NJ, Boniface K, Chan JR, et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol, 2007, 8: 950-957.
13.	Kolls JK, Lind　n A. Interleukin-17 family members and inflammation. Immunity, 2004, 21: 467-476.
14.	Aranami T, Yamamura T. Th17 cells and autoimmune encephalomyelitis( EAE/MS) . Allergol Int, 2008, 57: 115-120.
15.	Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates inflarmmation by producing interleukin 17. Nat Immunol,2005, 6: 1133-1141.
16.	Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17 -producing CD4 + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol, 2005 , 6: 1123 -1132.
17.	Xiong W, Zeng D, Xu Y, et al. Expression of interleukin-17 in lung and peripheral blood of asthmatic rats and the influence of dexamethasone. J Huazhong Univ Sci Technolog Med Sci, 2007, 27:498-500.
18.	Bullens DM, Truyen E, Coteur L, et al. IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir Res, 2006, 7: 135-139.
19.	王宏偉, 曲書強, 高君, 等. 哮喘患兒血清白細胞介素17、基質金屬蛋白酶-9 和免疫球蛋白E 水平測定的意義. 實用兒科臨床雜志, 2007, 4: 260-261.
20.	周慶濤, 孫永昌, 姚婉貞. 重度支氣管哮喘患者氣道炎癥及其與白細胞介素17 的關系. 中華結核和呼吸雜志, 2005, 9: 630-635.
21.	Nakae S, Komiyama Y, Nambu A, et al. Antigen-specific T cell sensitization is impaired in Il-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity, 2002, 17: 375 -387.
22.	Schnyder-Candrian S, Togbe D, Couilin I, et al. Interleukin-17 is a negative regulator of established allergic asthma. J Exp Med, 2006 ,203: 2715-2725.
23.	Pichavant M, Goya S, Meyer EH, et al. Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17 . J Exp Med, 2008, 205: 385 -393.
24.	Molet S, Hamid Q, Davoine F, et al. IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol, 2001, 108: 430-438.
25.	Prause O, Laan M, L　tvall J, et al. Pharmacological modulation of interleukin-17-induced GCP-2, GRO-alpha and interleukin-8 release in human bronchial epithelial cells. Eur J Pharmacol, 2003 , 462 :193-198.
26.	Jones CE, Chan K. Interleukin-17 stimulates the expression of interleukin-8, growth-related oncogene-alpha, and granulocytecolony-stimulating factor by human airway epithelial cells. Am J Respir Cell Mol Biol, 2002, 26: 748-753.
27.	Lind　n A, LaanM, Anderson GP. Neutrophils, interleukin-17A and lung disease. Eur Respir J, 2005, 25: 159-172.
28.	Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol, 2008, 8: 183-192.
29.	Imamura M, Okunishi K, Ohtsu H, et al. Pravastatin attenuates allergic airway inflammation by suppressing antigen-sensitization, IL-17 production, and antigen-presentation in the lung. Thorax, 2009 ,64: 44-49.

1. Katoh S, Kitazawa H, Shimosato T, et al. Cloning and characterization of Swine interleukin-17, preferentially expressed in the intestines. J Interferon Cytokine Res, 2004, 24: 553-559.
2. Li TS, Li XN, Chang ZJ, et al. Identification and functional characterization of a novel interleukin 17 receptor: a possible mitogenic activation through ras /mitogen-activated protein kinase signaling pathway. Cell Signal, 2006, 18: 1287-1298.
3. Rahman MS, Yamasaki A, Yang J, et al. IL-17A induces eotaxin-1 /CC chemokine ligand 11 expression in human airway smooth muscle cells: role ofMAPK ( Erk1/2, JNK, and p38) pathways. J Immunol,2006, 177: 4064-4071.
4. Patel DN, King CA, Bailey SR, et al. Interleukin-17 stimulates Creactive protein expression in hepatocytes and smooth muscle cells via p38MAPK and ERK1 /2-dependent NF-kappaB and C/EBPbeta activation. J Biol Chem, 2007, 282: 27229-27238.
5. Ferretti S, Bonneau O, Dubois GR, et al. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharideinduced airway neutrophilia: IL-15 as a possible trigger. J Immunol,2003, 170: 2106-2112.
6. Miljkovic DJ, Cvetkovic I, Vuckovic O, et al. The role of interleukin-17 in inducible nitric oxide synthase-mediated nitric oxide production in endothelial cells. Cell Mol Life Sci, 2003, 60 : 518 -525.
7. Henness S, van Thoor E, Ge Q, et al. IL-17A acts via p38 MAPK to increase stability of TNF-alpha-induced IL-8 mRNA in human ASM. Am J Physiol Lung Cell Mol Physiol, 2006, 290: L1283-L1290 .
8. Kao CY, Huang F, Chen Y, et al. Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/ NF-kappaB-dependent signaling pathway. J Immunol, 2005, 175: 6676-6685.
9. Happel KI, Zheng M, Young E, et al. Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection. J Immunol, 2003, 170: 4432-4436.
10. Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17 -producing CD4 + effector T cells develop via a liesge distinct from the T helper type 1 and lineages. Nat Immunol, 2005, 6: 123-132.
11. Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol, 2005, 6: 1133-1141.
12. Wilson NJ, Boniface K, Chan JR, et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol, 2007, 8: 950-957.
13. Kolls JK, Lind　n A. Interleukin-17 family members and inflammation. Immunity, 2004, 21: 467-476.
14. Aranami T, Yamamura T. Th17 cells and autoimmune encephalomyelitis( EAE/MS) . Allergol Int, 2008, 57: 115-120.
15. Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates inflarmmation by producing interleukin 17. Nat Immunol,2005, 6: 1133-1141.
16. Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17 -producing CD4 + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol, 2005 , 6: 1123 -1132.
17. Xiong W, Zeng D, Xu Y, et al. Expression of interleukin-17 in lung and peripheral blood of asthmatic rats and the influence of dexamethasone. J Huazhong Univ Sci Technolog Med Sci, 2007, 27:498-500.
18. Bullens DM, Truyen E, Coteur L, et al. IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir Res, 2006, 7: 135-139.
19. 王宏偉, 曲書強, 高君, 等. 哮喘患兒血清白細胞介素17、基質金屬蛋白酶-9 和免疫球蛋白E 水平測定的意義. 實用兒科臨床雜志, 2007, 4: 260-261.
20. 周慶濤, 孫永昌, 姚婉貞. 重度支氣管哮喘患者氣道炎癥及其與白細胞介素17 的關系. 中華結核和呼吸雜志, 2005, 9: 630-635.
21. Nakae S, Komiyama Y, Nambu A, et al. Antigen-specific T cell sensitization is impaired in Il-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity, 2002, 17: 375 -387.
22. Schnyder-Candrian S, Togbe D, Couilin I, et al. Interleukin-17 is a negative regulator of established allergic asthma. J Exp Med, 2006 ,203: 2715-2725.
23. Pichavant M, Goya S, Meyer EH, et al. Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17 . J Exp Med, 2008, 205: 385 -393.
24. Molet S, Hamid Q, Davoine F, et al. IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol, 2001, 108: 430-438.
25. Prause O, Laan M, L　tvall J, et al. Pharmacological modulation of interleukin-17-induced GCP-2, GRO-alpha and interleukin-8 release in human bronchial epithelial cells. Eur J Pharmacol, 2003 , 462 :193-198.
26. Jones CE, Chan K. Interleukin-17 stimulates the expression of interleukin-8, growth-related oncogene-alpha, and granulocytecolony-stimulating factor by human airway epithelial cells. Am J Respir Cell Mol Biol, 2002, 26: 748-753.
27. Lind　n A, LaanM, Anderson GP. Neutrophils, interleukin-17A and lung disease. Eur Respir J, 2005, 25: 159-172.
28. Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol, 2008, 8: 183-192.
29. Imamura M, Okunishi K, Ohtsu H, et al. Pravastatin attenuates allergic airway inflammation by suppressing antigen-sensitization, IL-17 production, and antigen-presentation in the lung. Thorax, 2009 ,64: 44-49.

Chinese Journal of Respiratory and Critical Care Medicine

白細胞介素17A在哮喘發病機制中的研究進展

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