【摘要】 目的 觀察原發性高血壓左心室肥厚患者的心律失常情況。 方法 對2000年1月-2009年10月收治的251例原發性高血壓患者進行超聲心動圖及Holter檢查，比較有左心室肥厚（left ventricular hypertrophy，LVH）及無LVH兩組各類心律失常的發生情況。 結果 LVH組各種心律失常的發生率與非LVH組比較，差異有統計學意義（Plt;0.01）。LVH組室性心律失常及復雜性室性心律失常的檢出率為83.33%和51.85%，明顯高于非LVH組（28.67%和9.09%），差異有統計學意義（Plt;0.01）。 結論 高血壓并發LVH與心律失常的發生有一定密切關系。【Abstract】 Objective To analyze the condition of arrhythmia in the patients with primary hypertension combined with left ventricular hypertrophy. Methods A total of 251 patients with primary hypertension from January 2000 to October 2009 were selected. All the patients had undergone the examinations of ultrasonic cardiogram, 12-lead electrocardiogram and Holter test to compare the incidence of arrhythmia between LVH and non-LVH group. Results There were significant differences in the incidences of arrhythmia between the two groups (Plt;0.01). Furthermore, the incidence of ventricular arrhythmias and complexity of ventricular arrhythmias of the patients in LVH group was 83.33% and 51.85% respectively, significantly higher than that in non-LVH group (28.67% and 9.09%; Plt;0.01). Conclusion Primary hypertension combined with LVH is relevant to arrhythmias.
As an intermediate phenotype for multiple cardiovascular diseases, left ventricular hypertrophy (LVH) benefits from early diagnosis, which allows for timely intervention to prevent worsening of the condition, mitigate severe complications like heart failure and arrhythmias, and consequently improve patient outcomes. Preliminary advances have been made using deep learning for the early diagnosis and identification of etiology in LVH. This paper reviews the pathophysiology, causes, and diagnostic standards for LVH, discusses the strengths and weaknesses of applying deep learning to diagnostic tools such as echocardiography, cardiac magnetic resonance imaging, and electrocardiogram, examines its use in prognostic evaluation, and concludes by summarizing current achievements and suggesting future research avenues.
目的:探討24 h平均脈壓(PP)對高血壓病患者左心室肥厚(LVH)的影響。方法:入選原發性高血壓病患者136 例,進行24 h 動態血壓監測和超聲心動圖檢查。根據24 h 平均脈壓水平各分為3組進行比較。結果:24 h平均脈壓與年齡、左心室重量指數、動脈僵硬度指數有顯著的相關性。結論:脈壓升高是老年高血壓病患者左心室肥厚的重要危險因素。
ObjectiveTo evaluate the effects of combined bisoprolol and candesartan therapy on left ventricular hypertrophy and left heart function in in elderly patients with hypertension.
MethodsFrom July 2011 to August 2012, 117 elderly inpatients or outpatients with hypertension in our hospital were randomly divided into trial group and control group. Patients in the control group received levamlodipine besylate and bisoprolol, and patients in the trial group received candesartan and bisoprolol.
ResultsThere was no statistical difference between the two groups at baseline. Three months later, there was no obvious difference of the blood pressure levels between the two groups (P>0.05). The parameters of left ventricular hypertrophy and left heart function were improved at the end of follow-up in both the two groups, but the parameters of the trial group improved better than the control group (P<0.05).
ConclusionIn the elderly patients with hypertension, the combined bisoprolol and candesartan or levamlodipine besylate and bisoprolol therapy can improve left ventricular hypertrophy and left heart function, and the results are better for the combination of bisoprolol and candesartan.
