【摘要】 目的 探討放射性核素骨顯像和血清前列腺特異抗原(PSA),堿性磷酸酶(ALP),骨特異性堿性磷酸酶(BAP)測定在前列腺癌骨轉移診斷中的價值。 方法 回顧性分析2006年10月-2009年10月50例前列腺癌(PCa)患者骨顯像結果及PSA、ALP、BAP測定結果。 結果 50例Pca患者骨顯像陽性率為70.0%。35例Pca骨轉移患者分布在PSAgt;20.0 ng/mL時占97.1%,BAPgt;20.1 μg/L時占88.6%,ALPgt;130.0 μg/L時占94.3%。血清PSA、ALP、BAP水平隨著放射性核素骨顯像分級的增高而逐步增高,呈高度正相關。 結論 放射性核素骨顯像仍然是目前診斷PCa骨轉移的主要方法;PSA、ALP、BAP亦是重要的輔助診斷指標;PSAgt;20.0 ng/mL時,患者應常規行全身骨顯像檢查。【Abstract】 Objective To explore the clinical value of radionuclide bone scintigraphy and measurements of serum prostate-specific antigen (PSA), alkaline phosphatase (ALP) and bone-specific alkaline phosphatase (BAP) in the diagnosis of bone metastasis in prostate cancer (PCa) patients from October 2006 to October 2009. Methods The results of bone scintigraphy, serum PSA, ALP and BAP were analyzed retrospectively in 50 PCa patients. Results The positive rate of bone scintigraphy was 70.0% in 50 PCa patients. In 35 patients with PCa bone metastasis, 97.1% of them were PSAgt;20.0 ng/mL, 88.6% were BAPgt;20.1 μg/L, and 94.3% were ALPgt;130.0 μg/L. The serum levels of PSA, ALP and BAP were increased step by step along with the advancement of bone metastatic grading from M0 to M3. They were significantly positively correlated. Conclusion Radionuclide bone scintigraphy is a major method in the diagnosis of bone metastasis in PCa patients currently. PSA, ALP and BAP are also important auxiliary diagnostic markers. Patients with the level of PSAgt;20.0 ng/mL should take a routine whole-body examination of bone scintigraphy.
摘要:目的:探討超聲與核素顯像在評價干燥綜合征(SS)腮腺受累情況中的價值和作用。方法:對65例SS病人分別進行超聲和核素顯像檢查。結果:超聲判為腮腺功能0級、I級、ⅡⅢ級、Ⅳ級的能力與核素顯像判為正常(χ2=0.075,Pgt;0.05)、輕度(χ2=0.12,Pgt;0.05)、中度(χ2=0.27,Pgt;0.05)、重度(χ2=0.097,Pgt;0.05)受損的能力一致,差異無統計學意義;核素發現單純攝取功能受損的超聲多表現為不均勻型、單純排泌功能受損的超聲多表現為結節型、攝取和排泌功能均受損的超聲多表現為纖維化型。結論:超聲檢查可作為SS患者腮腺受累情況評價的良好手段。Abstract: Objective: To quantitatively evaluate ultrasonography and radionuclide imaging in thediagnosis of parotid gland involvement in Sjogren syndrome (SS). Methods: Ultrasonography and radionuclide imaging were conducted on 65 cases with primary Sjogren syndrome. Results: There was no significant difference statistically between the ultrasonographic appearance of the parotid gland and radionuclide imaging (P gt;0. 05). Conclusion: As for diagnosis and evaluating the parotid gland of Sjogren syndrome, ultrasonography may be the useful choice.
摘要:目的:應用區域阻抗法測定慢性阻塞性肺疾病(COPD)患者的肺血流灌注及肺通氣分布的變化,與放射性核素肺顯像方法比較,探討肺區域阻抗方法的臨床應用價值。 方法: 測定對象為18例中重度COPD患者,均為男性,平均年齡63.8歲,應用肺區域阻抗法及放射性核素法,分別測定肺血流灌注及肺通氣的分布。〖HTH〗結果〖HTSS〗: 本研究發現肺區域阻抗法在測定肺血流灌注分布方面,僅在左下肺區域高于核素法測得的數值(Plt;0.05),余肺區測定結果相近,無顯著差異。在肺通氣的測定方面,阻抗法所得數值與核素法測得的數值有一定的不同,在左上、右上區域高于核素法測得的數值,在左中肺區測得的數值低于核素法測得的數值(Plt;0.05),余肺區測定結果相近,無顯著差異。結論: 雖然目前區域阻抗方法暫不能取代放射性核素的測定,但作為一種輔助手段,可簡便、快速了解肺內的通氣、血流等生理病理改變。Abstract: Objective: To evaluate the clinical capability of regional electric impedance pneumograph and scintigraphy in measurement of pulmonary perfusion and ventilation in patients with COPD. Methods: Thirtytwo patients with different respiratory diseases underwent regional electric impedance pneumograph and scintigraphy, the pulmonary perfusion and ventilation were obtained and recorded. Results:The pulmonary perfusion results got by regional electric impedance pneumograph in the left lower region was lower than the results measured by scintigraphy, there were significant difference (Plt;0.05), and no difference in other pulmonary region. The pulmonary ventilation results got by regional electric impedance pneumograph in the both upper region were higher and in the left middle region were lower than the results measured by scintigraphy, there were significant difference(Plt;0.05), and no difference in other pulmonary region. Conclusion:The result got by regional electric impedance pneumograph could not replace the result got by scintigraphy at present, but this is a quick, simple,and convenient measurement to get parameter of the pulmonary perfusion and ventilation.