Objective
To summarize research status of correlation of chronic lymphocytic thyroiditis (CLT) and papillary thyroid carcinoma (PTC), in order to provide a basis for early diagnosis, prognosis, and prevention of PTC.
Method
The literatures about the recent studies of the correlation of the CLT and PTC were reviewed according to the results searched from PubMed database, SpringerLink database, Web of Science database, Wanfang database, CNKI database, and VIP database.
Results
The most of patients with CLT combined with PTC are young women, the characteristics are multifocal and occult, the prognosis is good. Its genesis might be related to the ionizing radiation, iodine intake, endocrine disorders, immune disorders, molecular biology, and other factors. But there are still different controversies about its specific pathogenesis and surgical treatment.
Conclusions
CLT is closely related to PTC. However, relationship between CLT combined with PTC and changing regularity of molecular biology, pathogenesis, or prognosis needs further to be studied and followed-up for a longer-term.
The article focuses on the recent progress in foot and ankle surgery, including the diagnosis of disease, treatment protocols, outcomes, and evaluation tools as well as other innovations. New and accurate diagnostic modalities and measurements have undergone a breakthrough. Diagnostic modalities tend to be simpler and less expensive. Measurement tools also change to simpler and more accurate. The accuracy and efficacy of surgery and the minimally invasive method have become more popular and important. New treatments and basic research have also made breakthroughs.
ObjectiveTo review the development and clinical application of ankle prosthesis.MethodsThe recent literature on ankle prosthesis design and clinical application was reviewed and analyzed. ResultsCompared with the hip and knee prostheses, the ankle prosthesis develops slowly and has been developed to the third generation. The ankle joint has a special structure of multi-axis movement. The design of the first and second generations of prostheses is not conformed to the biomechanics of the ankle. The third generation of prosthesis is more conform to the characteristics of ankle biomechanics, with high postoperative survival rate and satisfactory clinical outcome. ConclusionAt present, the survival rate of ankle prosthesis is low, and there is still much room for improvement in biomechanics, materials, and other aspects.
Objective
To explore the application effects of innovative health education on patients undergoing ambulatory laparoscopic cholecystectomy (LC).
Methods
A total of 139 patients undergoing ambulatory LC from November to December 2016 were selected as the control group, receiving the traditional health education; and other 141 patients undergoing ambulatory LC from February to March 2017 were selected as the observation group, receiving the innovative health education. The two groups were followed up and observed 1 day, 2, and 28 days after the discharge, and the incidence rates of adverse reactions such as postoperative pain, bleeding and incision infection were measured, and the disease knowledge mastery, self-care skills, medication compliance and satisfaction to nursing and hospital were evaluated.
Results
The total incidence rate of adverse reactions was 7.8% in the observation group and 25.2% in the control group (P<0.001). Medication compliance from high to low was 90, 46 and 5 cases in the observation group and 59, 64 and 16 cases in the control group (P<0.001). In the observation group, the scores of disease knowledge mastery, self-care cognition, nursing satisfaction and hospital satisfaction were 93.4±5.5, 91.4±4.5, 96.4±3.7 and 98.1±3.7, respectively, which were higher than those in the control group (83.8±8.7, 83.2±9.1, 91.5±9.2 and 94.8±7.3, respectively) with statistical significance (P<0.001).
Conclusion
Innovative health education has certain application effects on ambulatory LC, and it can significantly improve disease knowledge mastery and self-care cognition, and help to ensure the medical quality and safety during perioperative period, and improve the patients’ satisfaction.
Objective
To summarize the research progress of biocompatibility and surface modification of nickel titanium shape memory alloys (Ni-Ti SMA).
Methods
The relative researches about Ni-Ti SMA at home and abroad were reviewed, collated, analyzed, and summarized.
Results
At present, Ni-Ti SMA as an internal fixation material has been widely used in clinic. It has the following advantages: the super elasticity, the shape memory characteristic, the good wear resistance, and the strong corrosion resistance. It also can effectively avoid the internal fixator rupture caused by stress shielding. After surface modification, the biocompatibility of Ni-Ti SMA has been improved.
Conclusion
The Ni-Ti SMA is the most promising alloy material for the long-term internal fixator because of its excellent material properties.
Objective
To analyze clinical and pathological features of patients with papillary thyroid carcinoma (PTC) with coexistent chronic lymphocytic thyroiditis (CLT).
Methods
The clinicopathologic data of 756 cases of PTC were collected from January 2014 to January 2017 in the First Affiliated Hospital, Xinjiang Medical University were collected. The patients were designed to observational group (PTC with coexistent CLT, n=194) and control group (simple PTC, n=562) according to whether CLT was diagnosed by pathology, then the clinical data, ultrasonic features, thyroid function, and pathological features in these two groups were compared.
Results
The proportion of the female patients, the proportions of theserum thyroid stimulating hormone and thyroid autoimmune antibodies (thyroglobulin antibody and thyroid peroxidase antibody), and the proportion of multifocal carcinoma in the observational group were significantly higher than those in the control group (P<0.05). There were no significant differences in the preoperative ultrasound, tumor diameter, thyroid capsule invasion, central lymph node metastasis, and TNM stage in these two groups (P>0.05). The results of the multivariate analysis showed that the female, serum thyroid autoimmune antibodies, and the multifocal carcinoma were the independent predictive factors of PTC with CLT (P<0.05).
Conclusions
There might be a certain correlation between PTC and CLT, PTC with coexistent CLT is more common in female patient and with multifocal carcinoma. With coexistent CLT does not increase invasion of PTC. This may be associated with limit of CLT to development of PTC nodules. It is speculated that CLT may be a protective factor of PTC.
