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        west china medical publishers
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        find Author "王健" 65 results
        • Commentary on “Hospital at Home versus In-patient Hospital Care”

          Release date:2016-09-07 11:23 Export PDF Favorites Scan
        • 裂孔性視網膜脫離早期并玻璃體出血一例

          Release date:2016-09-02 06:36 Export PDF Favorites Scan
        • 支氣管鏡介入治療在肺移植術后氣道并發癥的應用研究進展

          Release date:2025-02-08 09:53 Export PDF Favorites Scan
        • 頻域光相干斷層掃描對黃斑疾病的評價研究進展

          黃斑疾病是老年人的主要致盲原因之一,對黃斑疾病的精確診斷對指導治療及評價預后是至關重要的。光相干斷層掃描(OCT)具有高度的可重復性,可早期診斷和監測黃斑疾病。頻域OCT在傳統OCT功能基礎上利用頻域技術并結合寬帶光源的應用可以三維重建視網膜立體結構,具有分辨率高、掃描速度快、獲取數據量大等優點,可更加清楚準確的評價黃斑疾病。

          Release date:2016-09-02 05:42 Export PDF Favorites Scan
        • The Prevalence of Metabolic Syndrome and Correlation of Waist-to-hip Ratio and Body Mass Index with Metabolic Syndrome in Certain University

          Objective We aimed to describe the prevalence of metabolic syndrome, its epidemiological characteristics, and to analyse the relationship of waist-to-hip ratio (WHR) and body mass index (BMI) with metabolic syndrome (MS) among staff at Southeast University. Methods The data from the overall physical examination of 1979 staff were analyzed.Results The crude prevalence of MS were 21.7%,26.4% and 14.2% in the whole population, men and women respectively. The standardized rates were 14.7%,19.0% and 9.4%. The prevalence of MS in men was significantly higher than that in women(Plt;0.05). Both abdominal obesity and visceral obesity were positively correlated with the prevalence of MS(r=0.295, 0.248, P=0.000). Conclusion The prevalence of MS among staff of Southeast University has shown a significant increase in 2006. WHR and BMI are both correlated with the prevalence of MS.

          Release date:2016-08-25 03:35 Export PDF Favorites Scan
        • Role of stromal cell derived factor-1/CXC chemokine receptor 4 pathway in mesenchymal stem cells therapies in the management of diabetic retinopathy

          Mesenchymal stem cells (MSC) are considered to have important value in the treatment of various diseases because of their low immunogenicity, transferability, and strong tissue repair capacity. Stromal cell derived factor-1 (SDF-1) and its receptor CXC chemokine receptor 4 (CXCR4) pathway plays an important role in migration of MSC. The induction of homing of MSC to retina by regulating SDF-1/CXCR4 may exert the curative effect on diabetic retinopathy to greatest exent.

          Release date:2016-11-25 01:11 Export PDF Favorites Scan
        • 心搏驟停后的溶栓治療

          心搏驟停是臨床上常見的急癥,病死率很高。任何原因導致的心搏驟停或其他急性事件引起的嚴重心肺損害發生后,由于腦組織失去系統循環及腦氧輸送,將迅速導致不可逆性的缺氧-缺血性腦損傷,這也正是復蘇后期患者死亡的主要原因。心肺復蘇后,盡管存在足夠的系統循環容量,但腦組織常發生微循環再灌注衰竭,使組織缺血延長,進而導致并加重繼發性腦損傷,影響復蘇治療的遠期預后。因此,心肺復蘇成功的標志不僅僅是自主循環的恢復,其最終目的是保護并恢復完整的腦功能。溶栓治療無論是對冠狀動脈血栓形成或肺栓子的直接作用,還是對微循環再灌注的作用,均可能改善神經學后果,但由于懼怕嚴重出血并發癥,溶栓治療腦復蘇長期被視為禁忌。現對心搏驟停后是否行溶栓治療以及溶栓時機的選擇等研究內容作一綜述。

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        • Comparison of Remifentanil and Fentanyl during Induction of Pediatric Anaesthesia

          目的:觀察等效劑量瑞芬太尼和芬太尼誘導氣管插管對小兒血流動力學的影響。方法:40例擇期行全麻患兒隨機分為瑞芬太尼組和芬太尼組,麻醉誘導使用咪唑安定0.15mg/kg、丙泊酚2.5mg/kg、芬太尼2.5μg/kg或瑞芬太尼2μg/kg和維庫溴銨0.1mg/kg。分別于麻醉誘導前(T0)、誘導后2min(T1)、插管后1、2min(T2、T3)記錄心率、收縮壓和舒張壓。結果:兩組誘導前血流動力學指標相似。與T0時比較,兩組患兒T1時收縮壓、舒張壓均降低(Plt;0.05或Plt;0.01),心率均減慢(Plt;0.05或Plt;0.01);瑞芬太尼組T2.T3時收縮壓、舒張壓降低(Plt;0.05或Plt;0.01),心率減慢(Plt;0.05);芬太尼組T2、T3時收縮壓、舒張壓升高(Plt;0.05),心率增快(Plt;0.05)。與芬太尼組比較,瑞芬太尼組T1、T2和T3時收縮壓、舒張壓均降低(Plt;0.05),心率減慢(Plt;0.05)。結論:瑞芬太尼比等效劑量芬太尼能更好地抑制小兒全麻誘導氣管插管時的心血管反應。

          Release date:2016-09-08 09:56 Export PDF Favorites Scan
        • Awareness of thrombolytic therapy for acute ischemic stroke in inpatients with a history of stroke and with a high risk of stroke

          Objective To explore the awareness of thrombolytic therapy for acute ischemic stroke in inpatients with a history of stroke and with a high risk of stroke. Methods From January to August 2012, using self-designed questionnaire, trained neurologists conducted the face to face investigation in 500 inpatients with a high risk of stroke, including those with a history of stroke in Department of Neurology in the Second Affiliated Hospital of Chongqing Medical University. Results A total of 467 valid questionnaires were recovered. Only 16.1% (75/467) patients were aware of thrombolytic therapy for acute stroke, of whom 50.7% (38/75) knew the time window of thrombolytic therapy. Awareness of thrombolytic therapy was higher in patients aged 56-70 years, with a higher level of education and income, and in those who knew at least 3 stroke warning signs and those with a history of stroke. While awareness of the time window of thrombolytic therapy was higher in those unmarried or widowed and with a history of stroke. Multiple logistic regression analysis showed that awareness of thrombolytic therapy was independently associated with age, education level, knowledge of stroke warning signs and a history of stroke; awareness of the time window was associated with marital status and a history of stroke (P<0.05). Conclusions Inpatients with a history of stroke and with a high risk of stroke in the Department of Neurology have poor awareness of thrombolytic therapy for acute ischemic stroke. It is necessary to improve the level of patients’ knowledge about thrombolytic therapy for acute stroke by health education.

          Release date:2017-12-25 06:02 Export PDF Favorites Scan
        • Analysis of influence factor for the failure of anterior cruciate ligament reconstruction

          ObjectiveTo investigate the influence of gender, age, activity level, and diameter of graft on the anterior cruciate ligament (ACL) reconstruction.MethodsBetween February 2012 and June 2017, 179 cases (111 males and 68 females) with an average age of 30.0 years (range, 11-63 years) were included in study. The patients underwent internal fixator removal at 2 years or more after single bundle ACL reconstruction with hamstring tendon autografts. All patients were sports injuries. The time from injury to operation ranged from 3 days to 26 years (median, 120 days). Lachman test and pivot shift test were positive. Univariate analysis was conducted on gender, age, post-operative activity level (Tegner score at the time of internal fixator removal), diameter of graft, and number of graft strands, and logistic regression was used to conduct multivariate analysis to screen the independent risk factors.ResultsAll patients were followed up 24-90 months (mean, 29.1 months). At last follow-up, Lachman test was positive in 25 cases and pivot shift test was positive in 28 cases. The KT-2000 side-to-side difference was –1-7 mm (mean, 1.89 mm). Eleven patients (6.15%) failed after ACL reconstruction. Univariate and multivariate analyses showed that the age, gender, post-operative activity level, diameter of graft, and number of graft strands were not risk factors for the failure of ACL reconstruction (P>0.05).ConclusionThere was no significant difference in the risk for ACL reconstruction failure among age, gender, and activity level. ACL reconstruction failure rate cannot be reduced by increasing the number of graft strands to increase the diameter of grafts.

          Release date:2019-12-23 09:44 Export PDF Favorites Scan
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