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        west china medical publishers
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        • 中介素在心血管系統的研究進展

          【摘要】 中介素(intermedin,IMD)又稱腎上腺髓質素2,是降鈣素基因相關肽超家族的一員。IMD能夠無選擇性作用于降鈣素受體樣受體/受體活化修飾蛋白復合物,通過受體復合物上G蛋白的變構,激活下游的效應酶及離子通道,再進一步發揮生物學效應。IMD的作用廣泛,其對血管的作用主要包括血管生成作用、外周血管擴張作用、中樞升壓作用及抗血管鈣化作用;其對心臟的作用主要包括正性肌力作用、正性頻率作用、抗心肌肥厚的作用等。

          Release date:2016-09-08 09:26 Export PDF Favorites Scan
        • Survey of Occupational Exposures and Protective Condition in Operating Room for Interventional Therapy

          ObjectiveTo evaluate the occupational exposures and protective condition of medical staff in operating room for interventional therapy. MethodsFrom September to November in 2014, 46 medical staff in the operating room for interventional therapy were adopted to complete the occupational exposures and protection situation survey. After that, we analyzed and scored all the questionnaires. ResultsThe awareness of the medical staff about occupational exposures and occupational protection in the operating room was low; the awareness rates of doctors, nurses, and radiology technicians were 74.2%, 63.0% and 66.7%, respectively. The general condition of implement of occupational protection measures of the medical staff was bad, and the average rate of the doctors, nurses and radiology technicians was 51.3%, 43.9%, and 15.2%. ConclusionThe implement rates of occupational protection measures of the medical staff in Operating Room for interventional therapy differ much from the awareness rates. The rates in doctors and nurses are higher than that in radiology technicians. We should strengthen the education of radiation damage and protection measures in doctors, and enhance the training of iatrogenic injuries related knowledge in clinical radiology technicians to reduce occupational hazards.

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        • An Analysis of the Relationship between Pulse Pressure, Pulse Pressure Index and Hyperuricemia in Middle-aged and Aged Residents in Chengdu

          【摘要】 目的 分析成都地區中老年居民脈壓(pulse pressure, PP)及脈壓指數(pulse presure index,PPI)與高尿酸血癥(hyperuricemia,HUA)的關系。 方法 利用2007年5月代謝綜合征研究調查資料(共1 061人),依據PP[≤60 mm Hg(1 mm Hg=0.133 kPa)、gt;60 mm Hg]和PPI(≤0.450、gt;0.450)將人群分為正常組及增高組,分析兩組人群尿酸水平及HUA患病率,采用單因素回歸及logistic回歸分析PP及PPI與HUA關系。 結果 ①PP/PPI增高組血漿尿酸水平明顯高于PP/PPI正常組,差異有統計學意義(P=0.000)。②PP/PPI增高組HUA患病率明顯高于PP/PPI正常組,差異有統計學意義(P=0.026、0.027)。③單因素回歸和logistic回歸分析皆提示PP及PPI與HUA呈正相關。 結論 成都地區PP及PPI與血漿尿酸水平關系密切,PP/PPI增高可能是HUA的危險因素。【Abstract】 Objective To evaluate the relationship between pulse pressure (PP), pulse pressure index (PPI) and hyperuricemia (HUA) among middle-aged and aged residents in Chengdu. Methods Based on the level of PP [≤60 mm Hg (1 mm Hg=0.133 kPa),gt;60 mm Hg] and PPI (≤0.450,gt;0.450), We divided the 1 061 middle-aged or aged people into normal PP/PPI group and augmented PP/PPI group. All patients came from the survey for metabolic syndrome study in May 2007. We analyzed the distribution of serum uric acid (UA) and HUA, and analyzed the relationship between PP, PPI and HUA by using single-factor and logistic regression analysis. Results The index of UA in the augmented PP/PPI groups was higher than that in the normal groups with a significant difference (P=0.000). The prevalence of HUA in the augmented PP/PPI groups was statistically higher than that in the normal groups (P=0.026, 0.027). Single-factor and logistic regression analysis showed that PP and PPI were both positively correlated to HUA. Conclusion The abnormalities of PP and PPI are closely related to metabolism disorder in Chengdu, and high level of PP or PPI is probably risk factors for HUA.

          Release date:2016-09-08 09:26 Export PDF Favorites Scan
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