Objective
To investigate the utilization of platinum drugs in 21 hospitals of Chengdu from 2011 to 2014.
Methods
The utilization information of platinum drugs in 21 hospitals of Chengdu from 2011 to 2014 was extracted, and the dosage form of drugs, consumption sum, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) were analyzed statistically.
Results
From 2011 to 2014, the total consumption sums and DDDs of platinum drugs were increased year by year. The consumption sums of oxaliplatin were the highest, and the consumption sums of carboplatin were increased year by year. Oxaliplatin, nedaplatin, and lobaplatin were ranked first, second and fifth respectively in all the four consecutive years; the total DDDs of patinum drugs from 2011 to 2014 showed a trend of increase, DDDs of cisplatin were always ranked first, followed by oxaliplatin; DDC and sorting of platinum drugs were relatively stable, and B/A values of carboplatin and cisplatin were close to 1.00.
Conclusion
The utilization of platinum drugs in 21 hospitals of Chengdu is in accordance with the principle of safety, effectiveness, economy and convenience.
【摘要】 目的 探討慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）治療方案及藥學監護的內容。 方法 以2007年12月收治的1例COPD患者為例，結合COPD治療指南，為COPD急性加重期患者制定個體化的藥學監護計劃并實施全程的藥學監護。 結果 患者COPD急性加重期的藥物治療方案有效合理。通過全程的藥學監護，及時發現和解決了患者藥物治療的問題，為臨床合理用藥提供了意見。 結論 對COPD患者實施藥學監護具有可行性和實用性。【Abstract】 Objective To investigate the treatment and pharmaceutical care for chronic obstructive pulmonary disease (COPD) patients. Methods In December 2007, a patient with COPD was diagnosed, and based on the clinical data, COPD treatment guidelines were adopted to analyze treatment plans. For patients with acute exacerbation of COPD, individualized pharmaceutical care plan was proposed, and pharmaceutical care was performed during the whole course of disease. Results The drug treatment for the one patient with acute exacerbation of COPD was effective and reasonable. Treatment problems were observed and solved through pharmaceutical care which had given reasonable suggestions for medication. Conclusion The implementation of pharmaceutical care for COPD patients is feasible and practical.
【摘要】 目的 驗證臨床藥師對我院中藥注射劑合理使用進行干預的效果。 方法 對比分析2010年臨床藥師干預前后中藥注射劑的合理使用情況，隨機抽取2010年1-6月合格病歷1 000份，設為非干預組；隨機抽取2010年9月-2011年2月合格病歷1 000份，設為干預組；評估臨床藥師的干預作用。 結果 非干預組中藥注射劑的使用率為31.10%，干預組為19.00%，差異有統計學意義（χ2=38.991，P=0.000）；非干預組適應證不合理的為6.00%，干預組為2.10%，差異有統計學意義（χ2=19.570，P=0.000）；非干預組發生不良反應15例，干預組發生3例，兩組不良反應發生率差異有統計學意義（χ2=8.073，P=0.004）；中藥注射劑的用法用量趨于規范。 結論 臨床藥師對中藥注射劑臨床使用的干預行之有效，對促進醫院安全、有效、合理使用中藥注射劑起到了積極作用。【Abstract】 Objective To explore the effects of clinical pharmacists intervention on traditional chinese medicine injection. Methods Compared the rational usage of traditional Chinese medicine injection in 2010 after the intervention of clinical pharmacists. A total of 1 000 clinical case records from January to June 2010 were randomly selected and was named as the non-intervention group; another 1 000 clinical case records from September 2010 to February 2011 were randomly selected and was named as the intervention group. The effect of the clinical pharmacists were evaluated. Results The utilization rate of the Chinese medicine injection was 31.10% in non-intervention group and 19.00% in the intervention group with a significant difference between the two groups (χ2=38.991，P=0.000). The irrationality of indication was 6.00% in non-intervention group and 2.10 in the intervention group with a significant difference between the two groups （χ2=19.570，P=0.000）. The adverse reaction was found in 15 patients in non-intervention group and in three patients in the intervention group with a significant difference between the two groups（χ2=8.073，P=0.004）. The usage and dosage of Chinese traditional medicine injection was tend to be normative. Conclusion The intervention on traditional Chinese medicine injection by clinical pharmacists is effective, which is a important part in promoting the rational use of traditional Chinese medicine injection.
【摘要】 目的 驗證臨床藥師對外科預防使用抗菌藥物進行干預的效果。 方法 以臨床藥師督查記錄數據為基礎，將2010年1-3月238份病歷設為非干預組，2010年10—12月240份病歷設為干預組，建立評價標準，進行回顧性匯總、分析。 結果 通過干預，抗菌藥物使用率從干預前的100%下降為77.08%（χ2=63.633，P=0.000），抗菌藥物聯用情況減少（χ2=53.712，P=0.000），用藥時機和用藥療程有了較大改善，抗菌藥物費用下降（t=-5.235，P=0.000），住院醫療費用降低（t’=-12.280，P=0.000），住院天數減少（t=-5.071，P=0.000）。 結論 臨床藥師通過實施合理用藥干預對促進醫院安全、有效、經濟使用抗菌藥物起到了積極作用。【Abstract】 Objective To verify the effect of clinical pharmacists’ intervention in antibiotics used for Type I incision surgical prevention. Methods Based on the supervision and inspection recording data of clinical pharmacists, we arranged 238 medical records in the first quarter of 2010 as non-intervened group and 240 medical records in the fourth quarter of 2010 as intervened group, and then established evaluation criteria and conducted a retrospective study for analysis. Results Through intervention, the rate of using antibiotics decreased from the previous 100% to 77.08% (χ2=63.633, P=0.000), the use of combined antibiotics also decreased (χ2=53.712, P=0.000), the time of course of using antibiotics improved, medical expenses of the antibiotics were reduced (t=-5.235, P=0.000), hospitalization cost decreased (t=-12.280, P=0.000), and hospital stay was shortened (t=-5.071, P=0.000). Conclusion Clinical pharmacists’ intervention in rational use of drugs play a positive role in contribution to a safe, effective and economical application of antibiotics.
