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        west china medical publishers
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        find Author "付平" 54 results
        • Research advances in the application of artificial intelligence for the diagnosis and treatment of acute kidney injury

          Acute kidney injury (AKI) is a common critical illness in clinical practice, with complex etiologies, acute onset, and rapid progression. It not only significantly increases the mortality rate of patients, but also may progress to chronic kidney disease. Currently, its incidence remains high, and improving early diagnosis rate and treatment efficacy is a major clinical challenge. Artificial intelligence (AI), with its powerful data processing and analysis capabilities, is developing rapidly in medical field, providing new ideas for disease diagnosis and treatment, and showing great potential in revolutionizing the early diagnosis, condition assessment, and treatment decision-making models in the AKI field. This article will review the application progress of AI in AKI prediction, condition assessment, and treatment decision-making, so as to provide references for clinicians and promote the further application and development of AI in the AKI field.

          Release date:2025-07-29 05:02 Export PDF Favorites Scan
        • The interpretation of KDIGO 2017 clinical practice guideline update for the diagnosis, evaluation, prevention and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD)

          Release date:2017-08-17 10:28 Export PDF Favorites Scan
        • 糖尿病酮癥酸中毒橫紋肌溶解致急性腎功能衰竭一例

          【摘要】 目的 報道糖尿病酮癥酸中毒(DKA)橫紋肌溶解(RM)并致急性腎功能衰竭的臨床診治經驗。〖HTH〗方法〖HTSS〗 2009年10月8日收治1例DKA患者,病程中出現意識障礙、RM、急性腎功能衰竭,行連續性血液凈化治療。結果 48 h后患者意識障礙恢復,血肌酸激酶下降,酸中毒糾正,治療效果顯著。結論 提高對DKA患者發生RM的認識和常規肌酶譜的動態監測,做好早期診斷以及預防極其重要,是RM合并急性腎損傷(AKI)治療的關鍵,有利于提高糖尿病患者的生存率。

          Release date:2016-09-08 09:37 Export PDF Favorites Scan
        • RhoA/Rho相關卷曲螺旋形成的蛋白激酶信號通路與慢性腎臟疾病

          【摘要】 RhoA/Rho相關卷曲螺旋形成的蛋白激酶(ROCK)信號通路是細胞內重要的信號轉導通路,在慢性腎臟疾病的進展中起重要作用。腎間質纖維化是各種慢性腎臟疾病發展到終末期腎衰竭的共同途徑;糖尿病腎病是繼發性慢性腎臟疾病的主要病因。現就RhoA/ROCK信號通路在腎間質纖維化和糖尿病腎病發病機制中的作用作一綜述。

          Release date:2016-09-08 09:26 Export PDF Favorites Scan
        • A brief talk about integrated management strategy of chronic kidney disease in China

          Chronic kidney disease (CKD) has been highlighted as one of the most important public health problems due to sharply climbing incidence and prevalence. To efficiently attenuate the disease burden and improve the disease management, not only active and effective treatment should be administrated, but also comprehensive follow-up nursing management with innovative and evolving spirits should be implemented. Thus dynamic changes of diseases could be acquired in time and patients are under appropriate medical instruction as soon as possible. This editorial is based on quickly developing medical big data resources and advanced internet techniques, from both aspects of patients and health care providers, briefly talking about integrated management strategy of CKD and its future development in China.

          Release date:2019-08-15 01:18 Export PDF Favorites Scan
        • Current status of exercise rehabilitation in maintenance hemodialysis patients

          Patients undergoing maintenance hemodialysis are characterized with lower cardiorespiratory capacity and muscle atrophy, thus easily leading to a sedentary lifestyle. These patients are usually associated with lower quality of life and worse prognosis. Evidence indicates appropriate exercise rehabilitation plan could help maintenance hemodialysis patients achieve better health outcomes. However, there is still a lack of evidence data to precisely recommend exercise type, intensity, frequency and timing specially designed for maintenance hemodialysis patients. This article aims to summarize the existing expert consensus on exercise rehabilitation for maintenance hemodialysis patients, important considerations in the implementation process, factors that affect exercise rehabilitation, with a view to encouraging maintenance hemodialysis patients to participate in the development of appropriate exercise rehabilitation plan and maximize health benefits.

          Release date:2020-08-25 09:57 Export PDF Favorites Scan
        • 糖尿病腎病合并Ⅳ型腎小管性酸中毒二例

          Release date:2016-09-08 09:52 Export PDF Favorites Scan
        • Internal medicine department management during surgical treatment of secondary hyperparathyroidism based on multiple disciplinary team

          ObjectiveTo investigate the role of multiple disciplinary team (MDT) during surgical treatment of renal secondary hyperparathyroidism (SHPT), and identify management points of Departments of Nephrology and Endocrinology.MethodsThe data of patients with chronic kidney disease undergoing surgical treatment for SHPT in West China Hospital of Sichuan University between January 2009 and December 2018 were retrospectively collected. We explained the surgical treatment of MDT in the management of renal SHPT, and compared the changes before and after the establishment of MDT.ResultsA total of 187 patients including 101 males and 86 females were enrolled, with an average age of (47.60±11.28) years old and median dialysis vintage of 7 years. Under MDT, the number of patients with parathyroidectomy increased [(8.50±5.10) vs. (59.50±2.12) patients/year, P<0.001] and the completion rate of preoperative examinations were greatly improved (P<0.001). The success rate of surgery was also increased (86.8% vs. 97.5%, P=0.010). Proportion of patients who were admitted to the Department of Nephrology was significantly increased (39.7% vs. 84.9%, P<0.001). Most patients after surgery were transferred to the Department of Endocrinology (5.9% vs. 77.3%, P<0.001) to manage postoperative complications and metabolic bone disease, and thus normalized the management of SHPT.ConclusionsThe MDT contributes to management of renal SHPT, which is worthy of popularization and spreading. The management of internal medicine departments during surgical treatment of SHPT based on MDT is important, because they can be helpful to complete preoperative examinations and preoperative preparation as well as to alleviate postoperative complications.

          Release date:2019-08-15 01:18 Export PDF Favorites Scan
        • Internet of things technology in the management of chronic kidney disease

          Chronic kidney disease (CKD) has become a global public health problem because of its high prevalence, low awareness, poor prognosis, and high medical costs. Effective follow-up management can facilitate timely adjustment of the treatment of the CKD patients and delay the disease progression. The application of internet of things (IoT) technology in dynamic monitoring and telemedicine is helpful for the self-management of patients with chronic diseases, and can provide convenient, intelligent, and humanized medical and health services. In the future, with the rapid growth of demands of CKD management and innovations in information technology, new medical IoT industry will accelerate the intelligent development of CKD management. Multi-disciplinary and multi-industrial collaboration should be promoted to solve current challenges, such as evaluation of actual effectiveness, the system design and construction, and the accessibility of intelligent healthcare services, to ensure that IoT products can improve clinical outcomes, reduce medical expenditure, and lower disease burden.

          Release date:2019-08-15 01:18 Export PDF Favorites Scan
        • 新型抗炎介質消退素的生物效應及機制

          消退素是一類具有抗炎效果的內源性多不飽和脂肪酸衍生物,可分為E類消退素、D類消退素、阿司匹林觸發消退素等類型。消退素在多種組織器官的炎癥中顯示出較強的抗炎效果,同時還具有鎮痛、抗纖維化、改善胰島素抵抗等作用。而核因子-κB、絲裂原活化蛋白激酶、蛋白激酶B等通路可能介導上述生物效應。現就消退素的生物效應及機制的最新研究進展作一綜述。

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