【摘要】 目的 評價64層螺旋CT低劑量冠狀動脈血管成像的價值。 方法 2009年1-6月157例患者隨機分為3組,常規劑量組(A組)管電流量采用1 000 mAs,兩個低劑量組(B、C組)分別采用800、600 mAs。對3組的圖像質量、噪聲、CT劑量指數(CTDI)、劑量長度乘積(DLP)和有效劑量(ED)進行評估。 結果 A、B、C組圖像噪聲分別為20.50±3.23、23.02±3.05和26.28±2.58,組間差異均無統計學意義(Pgt;0.05);A、B、C組的CTDI分別為(58.7±0.23)、(46.98±2.27)、(35.28±3.56) mGy,DLP分別為(1 050.88±89.63)、(846.21±57.86)、(641.13±32.15) mGy?cm,ED分別為(14.78±2.56)、(11.85±1.87)、(8.98±1.15) mSv,B、C組的CTDI、DLP、ED均明顯低于常規劑量A組(Plt;0.05),C組的CTDI、DLP、ED均為3組中最低值。 結論 64層螺旋CT冠狀動脈血管檢查,采用600 mAs管電流量獲得的冠脈圖像既可滿足診斷需要,又可使患者接受的輻射劑量降低。【Abstract】 Objective To evaluate the best tube current for low-dose radiation CT in coronary artery imaging by 64-slices multi-detector CT. Methods From January to June 2009, a total of 157 consecutive patients were randomly divided into 3 groups: group A (conventional group): 1 000 mAs; group B: 800 mAs; group C: 600 mAs. The image quality, noise, CT dose index (CTDI), dose length product (DLP) and effective dose (ED) in each group were measured and compared respectively. Results The image noise scores in group A, B, and C were (20.50±3.23), (23.02±3.05) and (26.28±2.58), respectively. There was no statistically significant difference among the three groups in the two indexes (Pgt;0.05). The CTDI in group A, B and C were (58.7±0.23), (46.98±2.27), and (35.28±3.56) mGy, respectively; the DLP in each were (1 050.88±89.63), (846.21±57.86), and (641.13±32.15) mGy?cm, respectively; the Ed were (14.78±2.56), (11.85±1.87), and (8.98±1.15) mSv, respectively. All of the differences among the three groups in CTDI, DLP and ED were statistically significant (Plt;0.05). Conclusion The image with 600 mAs as tube current in the coronary artery imaging of 64-slices multi-detector CT could fulfill the need of the diagnosis, and the radiation dose is apparently lower than the conventional scan.
ObjectiveTo evaluate the value of 70 kV and sonogram-affirmed iterative reconstruction technique in CT examination for children with congenital heart disease.
MethodsThirty children with congenital heart disease who underwent CT scan between January and September 2014 were included in this study. According to the different tube voltage, they were randomly divided into group A (80 kV) and group B (70 kV), with fifteen in each. All the children were scanned on a dual-source-CT (Siemens Definition Flash). Group A used filtered back projection reconstruction. Group B used sonogram-affirmed iterative reconstruction. We measured and calculated the pulmonary artery signal-to-noise ratio at the level of main pulmonary artery window, the signal-to-noise ratio of the ascending aorta, noise ratio contrast between the pulmonary artery and erector spinae and between the ascending aorta and erector spinae. The image quality for congenital heart disease was assessed by two senior radiologists. The measurement of radiation dose included effective dose (ED), volume CT dose index (CTDIvol) and dose length product (DLP).
ResultsThere were no significant differences between group A and B in terms of pulmonary artery signal-to-noise ratio (14.54±3.77, 11.23±2.52), the signal-to-noise ratio of the ascending aorta (14.76±3.41, 12.31±3.47), the noise ratio contrast between pulmonary artery and erector spinae (12.04±3.96, 9.18±3.76) and between the ascending aorta and erector spinae (12.47±4.59, 9.77±4.41) (P > 0.05). There was significant difference between group A and group B in CTDIvol[(0.53±0.09), (0.38±0.03) mGy], DLP[(12.93±1.79), (6.67±0.72) mGy·cm], and ED[(0.34±0.05), (0.17±0.02) mSv] (P < 0.05).
ConclusionThe application of 70 kV and sonogram-affirmed iterative reconstruction technique in CT examination for children with congenital heart disease can significantly reduce the radiation dose without any influence on image quality.
For refractory epilepsy requiring surgical treatment in clinic, precise preoperative positioning of the epileptogenic zone is the key to improving the success rate of clinical surgical treatment. Although the use of electrical stimulation to locate epileptogenic zone has been widely carried out in many medical centers, the preoperative implantation evaluation of stereoelectroencephalography (SEEG) and the interpretation of electrical stimulation induced EEG activity are still not perfect and rigorous. Especially, there are still technological limitations and unknown areas regarding electrode implantation mode, stimulation parameters design, and surgical prognosis correlation. In this paper, the clinical background, application status, technical progress and development trend of SEEG-based stereo-electric stimulation-induced cerebral electrical activity in the evaluation of refractory epilepsy are reviewed, and applications of this technology in clinical epileptogenic zone localization and cerebral cortical function evaluation are emphatically discussed. Additionally, the safety during both of high-frequency and low-frequency electrical stimulations which are commonly used in clinical evaluation of refractory epilepsy are also discussed.
ObjectiveTo summarize the methods and research progress of imaging evaluation of liver iron concentration.MethodsThe current status and progress of different imaging techniques in liver iron overload research were reviewed by studying the relevant literatures at home and abroad. The methods for determining liver iron concentration and their advantages and disadvantages were summarized.ResultsThe imaging methods for determining liver iron concentration mainly included traditional non-enhanced CT and dual energy CT examination, magnetic resonance signal intensity ratio, relative signal intensity index, T2 and R2 values, magnetic resonance spectroscopy, T2* and R2* values, susceptibility weighted imaging, and quantitative susceptibility mapping.ConclusionLiver iron quantification imaging method, including dual-energy CT and magnetic resonance imaging could non-invasively and accurately assess the liver iron overload.